Product Name |
14.3.3 beta antibody |
Catalog No |
70R-7622 |
Size |
100 ug |
Price |
$ 595.00
|
Synonymns |
Polyclonal 14.3.3 beta antibody, Anti-14.3.3 beta antibody, 14-3-3 beta antibody |
Description |
Rabbit polyclonal Human 14.3.3 beta antibody |
Background |
The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. This plethora of interacting proteins allows 14-3-3 to play important roles in a wide range of vital regulatory processes, such as mitogenic signal transduction, apoptotic cell death, and cell cycle control. 14-3-3 alpha and beta mediate signal transduction by binding to phosphoserine containing proteins. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases. It may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. |
Immunogen |
14-3-3 beta antibody was raised in rabbit using a synthetic peptide for the Nterminal of Human 14-3-3 beta as the immunogen |
Host |
Rabbit |
Isotype |
IgG |
Specificity |
Human |
Cross Reactivity |
To be determined by end-user |
Method of Purification |
14-3-3 beta antibody was affinity purified using a synthetic peptide |
Source |
Serum |
Form & Buffer |
Supplied lyophilized from PBS, pH 7.4, with 1% BSA and 0.05% NaN3. Reconstitute with 1ml of distilled water. |
Storage |
Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at 20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
IHC, WB |
Usage Recommendations |
WB: 15 ug/ml |
