Product Name |
14.3.3 gamma protein |
Catalog No |
30R-1103 |
Size |
100 ug |
Concentration |
1 mg/ml |
Price |
$ 295.00
|
Synonymns |
YWHAG protein, 14-3-3 gamma protein,Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide protein, Tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, gamma polypeptide 14 3 3 protein gamma protein, 14 3 3 protein gamma subtype protein, 14 3 3gamma protein, 3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide protein, KCIP 1 protein, KCIP1 protein, Protein kinase C inhibitor protein 1 protein, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide. |
Description |
Purified recombinant Human 14.3.3 gamma protein |
Background |
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. Recombinant human YWHAG was expressed in E. coli and purified by using conventional chromatography techniques.
|
Species |
Human |
Residues |
1-247 amino acids: MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDS |
Molecular Weight |
28 kDa ( 247 aa), confirmed by MALDI-TOF. |
Protein Type |
Recombinant |
.
Grade & Purity |
> 95% by SDS - PAGE |
Form & Buffer |
Supplied as a liquid in 20mM Tris, pH 7.4. |
Storage |
Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
SDS-PAGE |
Endotoxin Levels |
< 1.0 EU per ug of protein (determined by LAL method) |
Additional Information |
14.3.3 gamma protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user. |
