Product Name |
14.3.3 sigma antibody (BSA/Azide Free) |
Catalog No |
10R-S101ap |
Size |
200 ug |
Concentration |
Batch dependent - please inquire should you have specific requirements |
Price |
$ 787.50
|
Synonymns |
Monoclonal 14.3.3 Sigma antibody, Anti-14.3.3 Sigma antibody, 14-3-3 Sigma antibody |
Description |
Mouse monoclonal 14.3.3 Sigma antibody (BSA/Azide Free) |
Background |
14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and
apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. 14-3-3 sigma shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo. |
Immunogen |
14.3.3 Sigma antibody (BSA/Azide-free) was raised in mouse using recombinant human 14-3-3 sigma protein as the immunogen. |
Host |
Mouse |
Isotype |
IgG1 kappa |
Clone |
1433S01 |
Specificity |
Human |
Cross Reactivity |
To be determined by end-user |
Method of Purification |
14.3.3 Sigma antibody (BSA/Azide Free) was purified by Protein G chromatography. |
Form & Buffer |
Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4. |
Storage |
Store at 4 deg C. |
Applications |
IF, IHC-F, IHC-P, IP |
Usage Recommendations |
IHC-F: 2-4 ug/ml, IHC-P: 2-4 ug/ml, IP: 2 ug/ml protein lysate |
Additional Information |
14.3.3 Sigma antibody with BSA and Azide is also availbale under catalog number 10R-S101a |
