Product Name |
14.3.3 zeta protein (His tag) |
Catalog No |
80R-1064 |
Size |
100 ug |
Concentration |
1 mg/ml |
Price |
$ 295.00
|
Synonymns |
YWHAZ protein, KCIP-1 protein, MGC111427 protein, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide protein, 14-3-3 zeta protein, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 14 3 3 protein zeta/delta protein, KCIP1 protein, Phospholipase A2 protein, Protein kinase C inhibitor protein 1 protein, Tyr-3/Trp-5 monooxygenase Activation protein, Zeta protein, Tyr3/Trp5 monooxygenase Activation protein, Zeta |
Description |
Purified recombinant Human 14.3.3 zeta protein |
Background |
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Recombinant human YWHAZ, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
|
Species |
Human |
Residues |
1-245 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMDK NELVQKAKLA EQAERYDDMA ACMKSVTEQG AELSNEERNL LSVAYKNVVG ARRSSWRVVS SIEQKTEGAE KKQQMAREYR EKIETELRDI CNDVLSLLEK FLIPNASQAE SKVFYLKMKG DYYRYLAEVA AGDDKKGIVD QSQQAYQEAF EISKKEMQPT HPIRLGLALN FSVFY |
Molecular Weight |
32 kDa (245 aa), confirmed by MALDI-TOF. |
Tag |
His tag |
Protein Type |
Recombinant |
.
Grade & Purity |
> 95% by SDS - PAGE |
Form & Buffer |
Supplied as a liquid in PBS, pH 7.4. |
Storage |
Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
SDS-PAGE |
Additional Information |
14.3.3 zeta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user. |
