Product Name |
26S Proteasome P52 Subunit antibody |
Catalog No |
10R-2432 |
Size |
5 ml |
Price |
$ 225.00
|
Synonymns |
Monoclonal 26S Proteasome P52 Subunit antibody, Anti 26S Proteasome P52 Subunit antibody |
Description |
Mouse monoclonal 26S Proteasome P52 Subunit antibody |
Background |
In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S proteasome is a 2.5-MDa molecular machine built from approximately 31 different subunits, which catalyzes protein degradation. It contains a barrel-shaped proteolytic core complex (the 20S proteasome), capped at one or both ends by 19S regulatory complexes, which recognize ubiquitinated proteins. The regulatory complexes are also implicated in unfolding and translocation of ubiquitinated targets into the interior of the 20S complex, where they are degraded to oligopeptides. |
Immunogen |
26S Proteasome P52 Subunit antibody was raised in mouse using 26S proteasomes purified from Xenopus laevis ovary as the immunogen. |
Host |
Mouse |
Isotype |
IgG1 |
Clone |
P52 (26S-17 |
Cross Reactivity |
Rat, Kangaroo Rat |
Form & Buffer |
Supplied in liquid form, contains 0.09% NaN3 |
Storage |
Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
WB |
Usage Recommendations |
WB: 1:5 - 1:10 |
