Product Name |
41BB ligand protein (His tag) |
Catalog No |
80R-1143 |
Size |
100 ug |
Concentration |
1 mg/ml |
Price |
$ 295.00
|
Synonymns |
Tumor necrosis factor ligand superfamily member 9 protein, TNFSF9 protein, 4-1BBL protein, CD137L protein, 4-1BB ligand protein, 4 1BB L protein, 4 1BB ligand protein, 4 1BBL protein, Cd137l protein, Cd157l protein, homolog of mouse 4 1BB L protein, homolog of mouse 4 1BBL protein, ILA ligand (TNF related) protein, Ly63l protein, receptor 4 1BB ligand protein, Tumor necrosis factor (ligand) superfamily member 9. |
Description |
Purified recombinant Human 41BB ligand protein |
Background |
4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
Species |
Human |
Residues |
71-254 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTG GLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPA |
Molecular Weight |
23.8 kDa (222aa), confirmed by MALDI-TOF. |
Tag |
His tag |
Protein Type |
Recombinant |
.
Grade & Purity |
> 95% by SDS - PAGE |
Form & Buffer |
Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 100mM NaCl, and 20% glycerol. |
Storage |
Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
SDS-PAGE |
Additional Information |
41BB ligand protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user. |
