Product Name |
5-Lipoxygenase antibody |
Catalog No |
70R-LR111A |
Size |
100 ul |
Concentration |
Batch dependent - please inquire should you have specific requirements |
Price |
$ 535.00
|
Synonymns |
Polyclonal 5 Lipoxygenase antibody, Anti-5 Lipoxygenase antibody, 5-Lipoxygenase antibody |
Description |
Affinity purified Rabbit polyclonal 5-Lipoxygenase antibody |
Background |
5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to
leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is
found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the
cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein
(FLAP) and with the 85 kDa cPLA2. |
Immunogen |
5 Lipoxygenase antibody was raised in rabbit using phosphopeptide corresponding to amino acid residues surrounding the phosphoserine 523 of human 5-lipoxygenase (5-LO) as the immunogen. |
Host |
Rabbit |
Specificity |
Human 5-lipoxygenase |
Cross Reactivity |
Rat |
Grade & Purity |
Affinity Purified |
Form & Buffer |
10mM HEPES, pH 7.5, with 150mM NaCl, 100 ug/ml BSA and 50% Glycerol. |
Storage |
Store at 4 deg C for short term storage. Aliquot and store at -80 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
WB |
Usage Recommendations |
Optimal conditions to be determined by end user |
