Product Name |
AATF antibody |
Catalog No |
10R-1233 |
Size |
50 ug |
Concentration |
100 ug/ml |
Price |
$ 395.00
|
Synonymns |
Monoclonal AATF antibody, Anti-AATF antibody, Apoptosis antagonizing transcription factor antibody, CHE-1 antibody, DED antibody, CHE1 antibody |
Description |
Mouse monoclonal AATF antibody |
Background |
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. |
Immunogen |
AATF antibody was raised in mouse using recombinant Apoptosis Antagonizing Transcription Factor |
Host |
Mouse |
Isotype |
IgG1 |
Clone |
AATF2B6 |
Specificity |
Human AATF |
Cross Reactivity |
Human. Other species not studied |
Method of Purification |
AATF antibody was purified using protein G column chromatography from culture supernatant of hybridoma
cultured in a medium containing bovine IgG-depleted
(approximately 95%) fetal bovine serum. |
Form & Buffer |
AATF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Storage |
Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
Applications |
Dot Blot |
Usage Recommendations |
To be optimized by the end user. |
Biohazard Information |
This antibody solution contains sodium azide (NaN )
as a preservative. There is a potential hazard that
NaN reacts with copper or lead to produce an explosive
compound. For safe disposal, the vial has to
be washed thoroughly with water. It is strongly adv |