Product Name |
ABCG2 antibody (biotin) |
Catalog No |
61R-1665 |
Size |
100 ug |
Concentration |
500 ug/ml |
Price |
$ 395.00
|
Synonyms |
Monoclonal ABCG2 antibody, Anti-ABCG2 antibody, ABCG 2 antibody, ABCG 2, ABCG-2 antibody, MXR antibody, ABCG2, ATP-binding cassette sub-family G member 2 antibody, ABCG-2, Bcrp1 antibody |
Description |
Mouse monoclonal ABCG2 antibody (biotin) |
Background |
The 5D3 monoclonal antibody reacts with the extracellular portion of the human ABCG2 protein, also known as Bcrp1 and MXR. The ABCG2 gene, a member of the multi-drug resistance family, is highly expressed on primitive ‘side-population’ stem cells, which are defined by the efflux of fluorescent dyes such as Rhodamine 123 and Hoechest 33342. In the bone marrow, about 0.05% of cells display the low fluorescence and are highly enriched for repopulating cells. The SP cells, which express low or undetectable levels of CD34, have been identified in multiple species. In addition, expression of ABCG2 appears to be highly conserved. |
Host |
Mouse |
Isotype |
IgG2b kappa |
Clone |
5D3 |
Specificity |
Human |
Form & Buffer |
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
Storage |
Store at 2-8 deg C. Do not freeze. Protect from light. |
Applications |
FC |
Usage Recommendations |
FC: = 0.5 ug/test |
Assay Information |
A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. |
