Product Name |
ATF7IP antibody |
Catalog No |
10R-1315 |
Size |
50 ug |
Concentration |
100 ug/ml |
Price |
$ 190.00
|
Synonyms |
Monoclonal ATF7IP antibody, Anti-ATF7IP antibody, FLJ10688 antibody, ATFIP-7, ATF7IP, ATFIP 7, p621 antibody, FLJ10139 antibody, ATFIP-7 antibody, ATFIP 7 antibody, Activating transcription factor 7 interacting protein antibody, MCAF antibody |
Description |
Mouse monoclonal ATF7IP antibody |
Background |
ATF7IP is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9'. The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. |
Immunogen |
ATF7IP antibody was raised in mouse using recombinant Human Activating Transcription Factor 7 Interacting Protein (Atf7Ip) |
Host |
Mouse |
Isotype |
IgG1 |
Clone |
2052C2a |
Specificity |
Human ATF7IP |
Cross Reactivity |
Human. Other species not studied |
Method of Purification |
ATF7IP antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Form & Buffer |
ATF7IP antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Storage |
Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
Applications |
Dot Blot |
Usage Recommendations |
To be optimized by the end user. |
Biohazard Information |
This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
