Product Name |
CD86 antibody (FITC) |
Catalog No |
61R-CD86aHUFT |
Size |
100 tests |
Concentration |
0.2 mg/ml |
Price |
$ 233.00
|
Synonyms |
Monoclonal CD86 antibody, Anti-CD86 antibody, CD86, CD 86, CD-86, CD-86 antibody, B72 antibody, CD 86 antibody |
Description |
Mouse monoclonal CD86 antibody (FITC) |
Background |
CD86, also known as B70/B7-2, is a 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily. It is expressed at high levels on resting monocytes and dendritic cells and at very low levels on resting B and T lymphocytes. Activation of B cells, T cells and monocytes leads to upregulation of CD86 expression. Like CD80, CD86 is a ligand of CD28 and CD152. The interactions of CD86 (and CD80) with CD28 provides important costimulatory signals to T cells activated via the CD3/TCR complex. CD86 is expressed earlier than CD80 and appears to dominate in the primary immune response. |
Immunogen |
CD86 antibody (FITC) was raised in mouse using CD86/B7-2 as the immunogen. |
Host |
Mouse |
Isotype |
IgG1 |
Clone |
BU63 |
Specificity |
Human CD86 |
Cross Reactivity |
To be determined by end-user |
Form & Buffer |
Supplied as a liquid in PBS, with NaN3 added as preservative. |
Storage |
Store at 4 deg C. |
Applications |
FC, IHC, IP, WB |
Usage Recommendations |
Optimal conditions to be determined by end user |
Biohazard Information |
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
