Product Name |
HDAC1 antibody |
Catalog No |
10R-1580 |
Size |
50 ug |
Concentration |
100 ug/ml |
Price |
$ 190.00
|
Synonyms |
Monoclonal HDAC1 antibody, Anti-HDAC1 antibody, HDA 1c antibody, HD1 antibody, HDA-1c antibody, DKFZp686H12203 antibody, HDAC1, HDA 1c, GON-10 antibody, HDA-1c, Histone deacetylase 1 antibody, RPD3 antibody, RPD3L1 antibody |
Description |
Mouse monoclonal HDAC1 antibody |
Background |
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumorsuppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
Immunogen |
HDAC1 antibody was raised in mouse using recombinant Human Histone Deacetylase 1 (Hdac1) |
Host |
Mouse |
Isotype |
IgG1 |
Clone |
730C6a |
Specificity |
Human HDAC1 |
Cross Reactivity |
Human, Mouse, Rat. Other species not studied |
Method of Purification |
HDAC1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Form & Buffer |
HDAC1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Storage |
Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
Applications |
Dot Blot, ICC, WB |
Usage Recommendations |
WB: 0.2-2 ug/ml |
Biohazard Information |
This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
