Product Name |
Adipophilin antibody |
Catalog No |
20R-AP002 |
Size |
100 ul |
Price |
$ 517.00
|
Synonyms |
Polyclonal Adipophilin antibody, Anti-Adipophilin antibody |
Description |
Guinea Pig polyclonal Adipophilin antibody |
Background |
Adipophilin / ADRP (a member of the PAT family) is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines (see e.g. Heid et al.; for review see e.g. Targett-Adams et al.); inducible by etomoxir. Enhanced expression of Adipophilin / ADRP is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis. |
Immunogen |
Adipophilin antibody was raised in guinea pig using a synthetic peptide corresponding to residues 1-29 of the N-terminus of human and murine adipophilin as the immunogen. |
Host |
Guinea Pig |
Specificity |
Human adipophilin |
Cross Reactivity |
Bovine, dog, human, mouse, rat |
Grade & Purity |
Whole antiserum |
Form & Buffer |
Supplied as whole antiserum with 0.09% NaN3. |
Storage |
Store at 4 deg C. |
Applications |
IHC-F, IHC-P, WB |
Usage Recommendations |
IHC-F: 1:100, IHC-P: 1:100, WB: 1:2,000 |
Biohazard Information |
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
Assay Information |
Adipocytes are negative. Also positively stained are lipid-storing CD 68-positive macrophages. |
