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UCP3 antibody ( 20R-UR003 )

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Product Name
UCP3 antibody
Catalog No
20R-UR003
Size
50 ug
Price
$ 250.00
Synonyms
Polyclonal UCP3 antibody, Anti-UCP3 antibody, UCP-3 antibody, UCP 3 antibody, Uncoupling Protein 3 antibody, UCP3, UCP -3, UCP 3 antibody, UCP -3 antibody, UCP 3
Description
Rabbit polyclonal UCP3 antibody
Background
Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and it is only 275 aa long. UCP3 has preferential expression in muscle and it is unaffected by cold acclimation.
Immunogen
UCP3 antibody was raised in rabbit using a 17 amino acid peptide sequence located at the 2nd and 3rd transmembrane domain of human UCP3 as the immunogen.
Host
Rabbit
Isotype
IgG
Specificity
Human
Cross Reactivity
To be determined by end-user
Method of Purification
UCP3 antibody was purified by affinity chromatography.
Form & Buffer
Lyophilized from PBS with 0.1% BSA, and 0.,02% merthiolate. Reconstitute with sterile deionised water.
Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Applications
ELISA, IF, IHC, WB
Usage Recommendations
ELISA: 1:10,000-1:100,000, HC: 2-20 ug/ml, IF: 2-20 ug/ml, WB: 1-10 ug/ml
Additional Information
This human UCP3 peptide sequences is 100% conserved in long and short form of human UCP3, 88% in monkey, 78% in humming bird, 76% in canine and pig, 70% in mouse, bovine, hamster, and 64% in rat UCP3. UCP31-P has no significant homology with UCP1-2 or UCP4-5.