Product Name |
uPAR antibody |
Catalog No |
70R-11825 |
Size |
100 ug |
Concentration |
500 ug/ml |
Price |
$ 395.00
|
Synonyms |
Polyclonal uPAR antibody, anti-uPAR antibody, URKR antibody, CD87 antibody, PLAUR antibody, Monocyte activation antigen Mo3 antibody, Urokinase plasminogen activator receptor antibody, CD_antigen antibody, UPAR antibody, CD87 antibody, Urokinase plasminogen activator surface receptor antibody, U-PAR antibody, MO3 antibody |
Description |
Goat polyclonal uPAR antibody |
Background |
uPAR is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator. Upon binding to uPAR, uPA converts the surface bound, large serum beta-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis. |
Immunogen |
uPAR antibody was raised in Goat using E coli expressed recombinant human uPAR as the immunogen. |
Host |
Goat |
Isotype |
IgG |
Cross Reactivity |
Human |
Method of Purification |
uPAR antibody was purified by affinity chromatography |
Form & Buffer |
Supplied in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA, 0.01% thimerosal |
Storage |
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Applications |
IP, Neutralization, WB |
Usage Recommendations |
IP: 5-10 ug/ml, Neutralization: 2-4 ug/ml, WB: 0.5-2 ug/ml |
