5-Lipoxygenase antibody (70R-LR111A)

Affinity purified Rabbit polyclonal 5-Lipoxygenase antibody

Synonyms Polyclonal 5 Lipoxygenase antibody, Anti-5 Lipoxygenase antibody, -Lipoxygenase -5 antibody, -Lipoxygenase 5, 5-Lipoxygenase, -Lipoxygenase 5 antibody, 5-Lipoxygenase antibody, -Lipoxygenase -5
Specificity Human 5-lipoxygenase
Cross Reactivity Rat
Applications WB
Immunogen 5 Lipoxygenase antibody was raised in rabbit using phosphopeptide corresponding to amino acid residues surrounding the phosphoserine 523 of human 5-lipoxygenase (5-LO) as the immunogen.

Specifications

Host Rabbit
Form & Buffer 10mM HEPES, pH 7.5, with 150mM NaCl, 100 ug/ml BSA and 50% Glycerol.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -80 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance 5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2.

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Availability: In stock

Price: $535.00
Size: 100 ul
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