ACAT1 antibody (10R-8652)

Mouse monoclonal ACAT1 antibody

Synonyms Monoclonal ACAT1 antibody, Anti-ACAT1 antibody, acetyl-CoA acetyltransferase 1 antibody, ACAT antibody, MAT antibody, T2 antibody, THIL
Applications ELISA, WB
Immunogen ACAT1 antibody was raised in Mouse using a recombinant human ACAT1 protein as the immunogen

Specifications

Host Mouse
Clone AT15E5
Isotype IgG1 kappa
Method of Purification ACAT1 antibody was purified by protein A affinity chromatography
Form & Buffer Supplied in liquid form in PBS, pH 7.4, containing 10% Glycerol, 0.01% Sodium Azide
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:1000, WB: 1:1000

Storage & Safety

Storage Store at 4 deg C for short term storage, for long term storage aliquot and store at -20 deg C, avoid repeated freeze thaw cycles.

General Information

Biological Significance ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.

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Availability: In stock

Price: $175.00
Size: 50 ul
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