Actin antibody (10R-2380)

Mouse monoclonal Actin antibody

Synonyms Monoclonal Actin antibody, Anti-Actin antibody, beta Actin antibody, ACTB antibody, Smooth Muscle Actin antibody, b-actin antibody, beta-actin antibody
Specificity Smooth Muscle
Cross Reactivity Bovine, Equine, Rat, Mouse, Chicken, Human
Applications IF, IHC, WB
Immunogen Actin antibody was raised in mouse using synthetic N- terminus decapeptide of alpha-smooth-muscle isoform of actin as the immunogen.

Specifications

Host Mouse
Clone ASM-1
Isotype IgG2a
Form & Buffer Supplied in liquid form, contains 0.09% NaN3 and 0.5% BSA in PBS pH 7.4

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells (the only known exception being nematode sperm) where it may be present at concentrations of over 100 uM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans. Actin is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells.

References
Add a Paper

Peter Trnka, Michael J. Hiatt, Larissa Ivanova, Alice F. Tarantal, Douglas G. Matsell

Phenotypic Transition of the Collecting Duct Epithelium in Congenital Urinary Tract Obstruction

Journal of Biomedicine and Biotechnology

Issue: 01/2010 DOI: 10.1155/2010/696034

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