Actin antibody (10R-2428)

Mouse monoclonal Actin antibody

Synonyms Monoclonal Actin antibody, Anti-Actin antibody, Cardiac Actin antibody, ACTB antibody, beta Actin antibody, beta-actin antibody, b-actin antibody
Specificity Cardiac Actin
Cross Reactivity Bovine, Rabbit, Chicken
Applications ELISA, IHC, WB
Immunogen Actin antibody was raised in mouse using synthetic NH2 terminus decapeptide of cardiac isoform of actin as the immunogen.

Specifications

Host Mouse
Clone AC1-20.4.2
Isotype IgG1
Form & Buffer Supplied in liquid form

Usage & Assay Information

Usage Recommendations ELISA 1:50, WB: 1:20

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Actin is a globular, roughly 42- kDa protein found in eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans. Actin is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells.

References
Add a Paper

Eva M. Oxford PhDa, Charles G. Danko PhDb, Bruce G. Kornreich DVM PhDa, Karen Maass PhDc, Shari A. Hemsley BSa, Dima Raskolnikov BSa, Philip R. Fox DVM MSd, Mario Delmar MD PhDe, N. Sydney Moïse

Ultrastructural changes in cardiac myocytes from Boxer dogs with arrhythmogenic right ventricular cardiomyopathy

Journal of Veterinary Cardiology

Volume: 13 Issue: 2 Page: 101-113 DOI: 10.1016/j.jvc.2011.03.002

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