ADI1 protein (His tag) (80R-2679)

Purified recombinant ADI1 protein (His tag)

Synonyms Acireductone dioxygenase 1 protein, APL1 protein, ARD protein, FLJ10913 protein, MTCBP1 protein, HMFT1638 protein, MTCBP-1 protein, SIPL protein, ADI1, ADI 1, ADI-1, ADI 1 protein, ADI-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of ADI1 protein (His tag) (80R-2679)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-179 aa: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSSMVL AWYMDDAPGD PRQPHRPDPG RPVGLEQLRR LGVLYWKLDA DKYENDPELE KIRRERNYSW MDIITICKDK LPNYEEKIKM FYEEHLHLDD EIRYILDGSG YFDVRDKEDQ WIRIFMEKGD MVTLPAGIYH RFTVDEKNYT KAMRLFVGEP VWTAYNRPAD HFEARGQYVK FLAQTA
Expression System E.coli
Purity > 90% pure
Molecular Weight 25.6 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Concentration 500 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles

General Information

Biological Significance ADI1 is an enzyme that belongs to the acireductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Also, it down-regulates cell migration mediated by MMP14. Recombinant human ADI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References
Add a Paper

Pratt J, Iddir M, Bourgault S, Annabi B.

Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma

Molecular Carcinogensis

PMID: 25640948 DOI: 10.1002/mc.22264

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Images

  • <div><font face=Calibri size=2>SDS-PAGE analysis of ADI1 protein (His tag) (80R-2679)</font></div>     | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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