Adiponectin protein (30R-AA040)

Purified recombinant Human Adiponectin protein

Synonyms Acrp-30 protein, Apm-1 protein, GBP-28 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Adiponectin protein corresponding to amino acids RGHHHHHHHH ETTTQGPGVL LPLPKGACTG WMAGIPGHPG HNGAPGRDGR DGTPGEKGEK GDPGLIGPKG DIGETGVPGA EGPRGFPGIQ GRKGEPGEGA YVYRSAFSVG LETYVTIPNM PIRFTKIFYN QQNHYDGSTG KFYCNIPGLY YFSYHITVYM KDVKVSLFKK DKAVLFTYDQ YQEKNVDQAS GSVLLHLEVG DQVWLQVYGD GDHNGLYADN VNDSTFTGFL LYHDTN.
Expression System Hi-5 cells
Purity > 97% pure
Form & Buffer Lyophilized from 20mM tris, pH 8.5, with 250mM L-arginine. Reconstitute in water to a concentration of 1.0 mg/ml.

Usage & Assay Information

Bioactivity Determined by a cytotoxic assay using M1 cells. The ED50 for this effect is 3.0-6.0 ug/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Adiponectin is an adipose-derived secreted protein containing 226 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity.

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Availability: In stock

Price: $225.00
Size: 25 ug
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