AGR3 protein (His tag) (80R-1852)
Purified recombinant AGR3 protein
|Synonyms||Anterior gradient protein 3 homolog protein, hAG-3 protein, PDIA18 protein, BCMP11 protein, AGR-3, AG3 protein, AGR3, AGR 3 protein, AGR-3 protein, HAG3 protein, AGR 3|
Coomassie Blue stained SDS-PAGE of AGR3 protein (His tag) (80R-1852)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||22-166 amino acids: MGSSHHHHHH SSGLVPRGSH MGSMIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL|
|Purity||> 90% pure|
|Molecular Weight||19.5 kDa (169aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||AGR3, also known as anterior gradient protein 3 homolog precursor, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Recombinant human AGR3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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