AIPL1 antibody (10R-3223)

Mouse monoclonal AIPL1 antibody

Synonyms Monoclonal AIPL1 antibody, Anti-AIPL1 antibody, Aryl hydrocarbon receptor interacting protein-like 1 antibody, LCA4 antibody, AIPL2 antibody, AIPL1, AIPL 1, AIPL-1, AIPL 1 antibody, AIPL-1 antibody
Cross Reactivity Human
Applications FC, IF, WB
Immunogen AIPL1 antibody was raised in mouse using a full length recombinant protein of human AIPL1 (NP_055151) produced in HEK293T cells, as the immunogen.

Images

Flow Cytometric analysis using AIPL1 antibody (10R-3223)

Flow Cytometric analysis of HEK293T cells transfected with either recombinant AIPL1 protein (red) or empty vector (blue) stained using AIPL1 antibody

Specifications

Host Mouse
Clone 2D11
Isotype IgG1
Method of Purification AIPL1 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 500 ug-1 mg/ml

Usage & Assay Information

Usage Recommendations FC: 1:100, IF: 1:100, WB: 1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA.

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Images

  • Flow Cytometric analysis using AIPL1 antibody (10R-3223) | Flow Cytometric analysis of HEK293T cells transfected with either recombinant AIPL1 protein (red) or empty vector (blue) stained using AIPL1 antibody
  • Western Blot analysis using AIPL1 antibody (10R-3223) | Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant AIPL1 protein (Right) or empty vector (Left) detected with AIPL1 antibody
  • Immunofluorescent staining using AIPL1 antibody (10R-3223) | Immunofluorescent staining of COS7 cells transiently transfected with recombinant AIPL1 protein using AIPL1 antibody

Availability: In stock

Price: $395.00
Size: 100 ul
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