AKR1A1 antibody (10R-3263)

Mouse monoclonal AKR1A1 antibody

Synonyms Monoclonal AKR1A1 antibody, Anti-AKR1A1 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, Alcohol dehydrogenase [NADP+] antibody, Alcohol dehydrogenase antibody, Aldehyde reductase antibody, aldo-keto reductase family 1 member A1 antibody, AKR1A1, AKRA 1, AKRA-1, AKRA 1 antibody, AKRA-1 antibody
Cross Reactivity Human
Applications IHC, WB
Immunogen AKR1A1 antibody was raised in mouse using a full length recombinant protein of human AKR1A1 (NP_006057) produced in HEK293T cells, as the immunogen.

Images

Immunohistochemical staining using AKR1A1 antibody (10R-3263)

Immunohistochemical analysis of AKR1A1 protein in paraffin embedded Human liver tissue using AKR1A1 antibody

Specifications

Host Mouse
Clone 3C7
Isotype IgG2a
Method of Purification AKR1A1 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 500 ug-1 mg/ml

Usage & Assay Information

Usage Recommendations IHC: 1:50, WB: 1:1000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance AKR1A1 is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65% identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

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Images

  • Immunohistochemical staining using AKR1A1 antibody (10R-3263) | Immunohistochemical analysis of AKR1A1 protein in paraffin embedded Human liver tissue using AKR1A1 antibody
  • Western Blot analysis using AKR1A1 antibody (10R-3263) | Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant AKR1A1 protein (Right) or empty vector (Left) detected with AKR1A1 antibody

Availability: In stock

Price: $395.00
Size: 100 ul
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