AKT2 antibody (10R-1920)
Mouse monoclonal AKT2 antibody
|Synonyms||Monoclonal AKT2 antibody, Anti-AKT2 antibody, Protein kinase B beta antibody, V-akt murine thymoma viral oncogene homolog 2 antibody, AKT2, AKT 2, AKT-2, AKT 2 antibody, AKT-2 antibody|
|Cross Reactivity||Human, Rat, Monkey|
|Applications||ELISA, IF, WB|
|Immunogen||AKT2 antibody was raised in Mouse using a purified recombinant fragment of human Akt2 expressed in E. coli as the immunogen.|
Immunofluorescent staining using Western Blot analysis using AKT2 antibody (10R-1920) (AKT2 antibody)
Immunofluorescence analysis of PANC-1 (left) and Hela (right) cells using AKT2 antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||AKT2 belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.|
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