alpha 2 Macroglobulin protein (30C-CP3005)

Purified native Human alpha 2 Macroglobulin protein

Synonyms A2M protein, alpha Macroglobulin 2, S863 7 protein, alpha Macroglobulin-2 protein, alpha 2 Macroglobulin, alpha 2 M protein, alpha Macroglobulin-2, DKFZp779B086 protein, alpha 2M protein, alpha Macroglobulin 2 protein, CPAMD5 protein, FWP007 protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human plasma
Purity > 95% pure
Molecular Weight 725 kDa
Form & Buffer Lyophilized from 30mM Na3PO4, pH 7.0, with glycine as a stabilizer.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance A major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a proteinase inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases.

References
Add a Paper

Masmudur M. Rahmana, David Jengc, Rajkumari Singhb, Jake Coughlinc, Karim Essanic, Grant McFadden

Interaction of human TNF and β2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L

Virology

Volume: 386 Issue: 2 Page: 462-468 DOI: 10.1016/j.virol.2009.01.026

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Availability: In stock

Price: $154.80
Size: 1 mg
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