alpha Actin antibody (muscle) (10R-7940)

Mouse monoclonal alpha Actin antibody (muscle)

Synonyms Monoclonal alpha Actin antibody, Anti-alpha Actin antibody, alpha Actin 1 antibody, alpha Actin, alpha Actin
Specificity Reacts with alpha-muscle and gamma-smooth muscle actin. It is also reactive in myofibroblasts. Does not react with epithelial, endothelial, neural or normal connective tissue cells.
Cross Reactivity Chicken, Human, Monkey, Rabbit, Rat, Swine, Zebrafish
Applications ELISA, IHC, IHC-F, IHC-P, WB
Immunogen alpha Actin antibody (muscle) was raised in Mouse using an SDS-extracted protein fraction from human myocardium as the immunogen.

Specifications

Host Mouse
Clone HHF35
Isotype IgG1
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:200-1:1000, WB: 1:1000-1:5000

General Information

Biological Significance The complex ultrastructure of cells--their shape and internal structure--and the many motions of cells are largely supported by filaments of actin. A tangle of cross-linked actin filaments fills the cytoplasm of animal, plant and fungal cells, forming a "cytoskeleton" that gives the cell shape and form and provides a scaffold for organization. Tightly bundled actin filaments provide a sturdy backbone to extrude structures from the cell surface, such as the pseudopods used by amoebas for crawling and the finger-like microvilli of intestinal cells, which extend into the digestive tract and absorb nutrients.

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Availability: In stock

Price: $370.00
Size: 100 ug
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