alpha beta Synuclein antibody (10R-1043)
Mouse monoclonal alpha, beta Synuclein antibody
|Synonyms||Monoclonal alpha beta Synuclein antibody, Anti-alpha, Non A beta component of AD amyloid antibody, Synuclein beta antibody, beta-Synuclein antibody, NACP antibody, beta synuclein antibody, PARK1 antibody, SNCB protein antibody, Parkinson disease familial 1 antibody, alpha synuclein antibody, SNCA antibody, b synuclein antibody, Non A4 component of amyloid precursor antibody, PD1 antibody, a antibody, Synuclein alpha antibody, SNCB antibody, PARK4 antibody|
|Cross Reactivity||Human, Mouse, Rat|
|Immunogen||alpha, beta Synuclein antibody was raised in mouse using recombinant human a-synuclein (119-140aa) purified from E. coli as the immunogen.|
Western Blot analysis of alpha, beta Synuclein antibody (10R-1043)
The recombinant human synuclein family (alpha-,beta- and gamma-) (each 20ng), Mouse brain and Rat brain (30 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human alpha,beta-synuclein (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
|Method of Purification||alpha, beta Synuclein antibody was purified by protein-G affinity chromatography|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.|
Usage & Assay Information
|Usage Recommendations||WB: 1:1000-1:2,000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Anti-human alpha, beta-synuclein antibody, clone 3B6, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human beta-synuclein protein. alpha-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.|
Sorry, but there are no references currently for this product.
Sorry there are currently no reviews for this product