alpha Catenin antibody (10R-7958)

Mouse monoclonal alpha Catenin antibody

Synonyms Monoclonal alpha Catenin antibody, Anti-alpha Catenin antibody, Cadherin associated protein antibody, Catenin beta 1 antibody, Catenin beta-1 antibody, CATNB antibody, CTNNB antibody, CTNNB1 antibody, alpha Catenin
Specificity Recognizes an epitope located between residues 164-177 of the human alphaT-catenin protein
Cross Reactivity Human
Applications FC, IHC, IP, WB
Immunogen alpha Catenin antibody was raised in Mouse using a synthetic peptide corresponding to amino acids 164-177 of the human alphaT-catenin protein including an additional N-terminal cysteine (CVANKSDLQKTYQKL) coupled to keyhole limpet hemocyanin as the immun

Specifications

Host Mouse
Clone 892_24D2S
Isotype IgG2a
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage & Assay Information

Usage Recommendations IHC: 1:25-1:50, WB: 1:100-1:1000

General Information

Biological Significance Beta-catenin (or beta-catenin) is a protein that in humans is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. beta-catenin is a subunit of the cadherin protein complex and has been implicated as an integral component in the Wnt signaling pathway. beta-Catenin is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. beta-Catenin also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

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Availability: In stock

Price: $385.00
Size: 100 ug
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