alpha Crystallin B antibody (10R-1030)

Mouse monoclonal alpha Crystallin B antibody

Synonyms Monoclonal alpha-Crystallin B antibody, Anti-alpha-Crystallin B antibody, Cryab antibody, Crya-2 antibody, Crystallin alpha B antibody, Crya2 antibody
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, WB
Immunogen alpha Crystallin B antibody was raised in mouse using recombinant human Crystallin alpha B (1-175 aa) purified from E. coli as the immunogen.


Host Mouse
Clone 2E8
Isotype IgG2b kappa
Source Anti-human Crystallin alpha B antibody, clone 2E8, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant Crystallin alpha B.
Method of Purification alpha Crystallin B antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance alpha-Crystallins are composed of two gene products; alpha-Crystallin A and B, for acidic and basic, respectively. alpha-Crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-Crystallin A and B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. alpha-Crystallin B is expressed widely in many tissues and organs and occurs in many neurological diseases.

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Availability: In stock

Price: $265.00
Size: 100 ul
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