alpha Synuclein A53T protein (30R-1003)
Purified recombinant Human alpha Synuclein A53T protein
|Synonyms||Alpha synuclein protein, Non-A-beta component of alzheimers disease amyloid protein, NACP protein, MGC64356 protein, Non-A beta component of AD amyloid protein, , precursor of PARK 1 protein, PD1 protein, SNCA protein, alpha-Synuclein protein, alphaSYN protein, Non A4 component of amyloid precursor protein, PARK4 protein, PARK 4 protein, PD 1 protein, MGC110988 protein, PARK1 protein, Synuclein alpha protein, MGC105443 protein, Non-A4 component of amyloid precursor protein, Parkinson disease familial 1 protein, Non A beta component of AD amyloid protein, Alpha-synuclein isoform NACP140 protein, MGC127560 protein|
Coomassie Blue stained SDS-PAGE of alpha Synuclein A53T protein (30R-1003)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA|
|Purity||> 95% pure|
|Molecular Weight||14.4 kDa (140 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid In 20mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||A Parkinson?s disease-related point mutant (A53T) of alpha-synuclein. A53T mutant of alpha-synuclein was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques.|
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