alpha Synuclein E46K protein (30R-1012)

Purified recombinant Human alpha Synuclein E46K protein

Synonyms Parkinson disease familial 1 protein, PD1 protein, Non-A4 component of amyloid precursor protein, alpha synuclein E46k protein, PD 1 protein, Alpha synuclein protein, alphaSYN protein, Non A beta component of AD amyloid protein, Non A4 component of amyloid precursor protein, Synuclein alpha protein, MGC110988 protein, alpha-synuclein e46k protein, MGC64356 protein, NACP protein, Non-A-beta component of alzheimers disease amyloid protein, precursor of PARK 1 protein, alpha-Synuclein protein, Non-A beta component of AD amyloid protein, MGC105443 protein, SNCA protein, MGC127560 protein, Alpha-synuclein isoform NACP140 protein, PARK4 protein, PARK1 protein, , PARK 4 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of alpha Synuclein E46K protein (30R-1012)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
Expression System E.coli
Purity > 95% pure
Molecular Weight 14.4 kDa (140 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
Form & Buffer Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0.1 M NaCl.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Alpha-synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate(E) to lysine(K). Recent studies have shown that this mutant(E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia(DLB). Alpha-synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of alpha Synuclein E46K protein (30R-1012) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $180.00
Size: 100 ug
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