alpha1 antichymotrypsin antibody (10R-8449)

Mouse monoclonal alpha1 antichymotrypsin antibody

Synonyms Monoclonal alpha1 antichymotrypsin antibody, Anti-alpha1 antichymotrypsin antibody, SERPINA3 antibody, serpin peptidase inhibitor antibody, clade A (alpha-1 antiproteinase antibody, antitrypsin) antibody, member 3 antibody, AACT antibody, ACT antibody, alpha-1-antichymotrypsin antibody, BOS_20523 antibody, cell growth-inhibiting gene 24/25 protein antibody, GIG24 antibody, GIG25 antibody, growth-inhibiting protein 24 antibody, growth-inhibiting protein 25 antibody, serine (or cysteine) proteinase inhibitor antibody, clade A (alpha-1 antiproteinase antibody, antitrypsin) antibody, member 1 antibody, serine (or cysteine) proteinase inhibitor antibody, clade A antibody, member 3 antibody, serine proteinase inhibitor antibody, clade A antibody, member 1 antibody, serpina1 antibody, serpin A3 antibody, serpin A3-5 antibody, SERPINA3-5 antibody, serpin peptidase inhibitor antibody, clade A antibody, member 3 antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen alpha1 antichymotrypsin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using alpha1 antichymotrypsin antibody (10R-8449)

Specifications

Host Mouse
Clone 71A1
Isotype IgG1 kappa
Method of Purification alpha1 antichymotrypsin antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance alpha-1-antichymotrypsin (ACT) is a glycoprotein with a molecular weight of 55~68 kDa and 25% by weight of various sugars, whose heterogeneity results in variation of molecular weight. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. Plasma ACT levels might increase rapidly more than 5-fold during an acute phase reaction, ACT has been shown to promote Abeta polymerization in vitro and in vivo, and levels of ACT protein in plasma and cerebrospinal fluid from Alzheimer's patients have been found to correlate with progression of dementia.

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Images

  • Western Blot analysis using alpha1 antichymotrypsin antibody (10R-8449) |

Availability: In stock

Price: $295.00
Size: 100 ul
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