alpha1 antitrypsin antibody (10R-8458)

Mouse monoclonal alpha1 antitrypsin antibody

Synonyms Monoclonal alpha1 antitrypsin antibody, Anti-alpha1 antitrypsin antibody, SERPINA1 antibody, serpin peptidase inhibitor antibody, clade A (alpha-1 antiproteinase antibody, antitrypsin) antibody, member 1 antibody, A1A antibody, A1AT antibody, AAT antibody, alpha-1-antiproteinase antibody, alpha 1 antitrypsin antibody, alpha-1 antitrypsin antibody, alpha-1-antitrypsin antibody, alpha-1-antitrypsin null antibody, alpha-1-antitrypsin precursor-like protein antibody, alpha-1-antitrypsin (protease inhibitor) antibody, alpha1AT antibody, alpha-1-PI antibody, alpha-1 protease inhibitor antibody, alpha-1-protease inhibitor antibody, alpha-1-proteinase inhibitor antibody, BOS_20452 antibody, EGK_18500 antibody, Pi antibody, PI1 antibody, PRO0684 antibody, PRO2275 antibody, protease inhibitor 1 antibody, protease inhibitor 1 (anti-elastase) antibody, alpha-1-antitrypsin antibody, protease inhibitor 1 (anti-elastase antibody, antitrypsin antibody, alpha-1) antibody, serine (or cysteine) proteinase inhibitor antibody, clade A (alpha-1 antiproteinase antibody, antitrypsin) antibody, member 1 antibody, serine (or cysteine) proteinase inhibitor antibody, clade A (alpha-1antiproteinase antibody, antitrypsin) antibody, member 1 antibody, serine (or cysteine) proteinase inhibitor antibody, clade A antibody, member 1 antibody, serine (or cysteine) proteinase inhibitor antibody, clade A antibody, member 1d antibody, serine protease inhibitor alpha 1 antibody, serine proteinase inhibitor antibody, clade A antibody, member 1 antibody, serpin A1 antibody, serpina1d antibody, Spi1 antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen alpha1 antitrypsin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using alpha1 antitrypsin antibody (10R-8458)

Specifications

Host Mouse
Clone 48D2
Isotype IgG1 kappa
Method of Purification alpha1 antitrypsin antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:4000, IHC-P

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance alpha1-antitrypsin, 52 kDa, is the prototypic member of the serine protease inhibitor (serpin) superfamily, which have a major role in inactivating neutrophil elastase and other proteases to maintain protease-antiprotease balance. The protein is synthesized mainly in the liver, but exerts its main function in the lung where it inhibits a variety of serine proteases, but primarily neutrophil elastase. It provides more than 90% of the antiproteolytic shield of the lower respiratory tract protecting the elastic tissue from degradation. Disorders of the enzyme include alpha 1-antitrypsin deficiency, a hereditary disorder in which lack of alpha 1-antitrypsin leads to uninhibited tissue breakdown during inflammation. This causes pulmonary emphysema and leads to liver cirrhosis in severe cases.

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Images

  • Western Blot analysis using alpha1 antitrypsin antibody (10R-8458) |

Availability: In stock

Price: $295.00
Size: 100 ul
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