Amyloid beta 40 antibody (10R-8435)

Mouse monoclonal Amyloid beta 40 antibody

Synonyms Monoclonal Amyloid beta 40 antibody, Anti-Amyloid beta 40 antibody, APP antibody, amyloid beta (A4) precursor protein antibody, AAA antibody, ABETA antibody, ABPP antibody, ad1 antibody, Adap antibody, AG antibody, alzheimer disease amyloid A4 protein homolog antibody, alzheimer disease amyloid protein antibody, amyloid A4 antibody, amyloid beta (A4) precursor protein (peptidase nexin-2 antibody, Alzheimer disease) antibody, amyloid beta (A4) precursor protein (peptidase nexin-II antibody, Alzheimer disease) antibody, amyloid beta (A4) precursor protein (protease nexin-II antibody, Alzheimer disease) antibody, amyloid beta A4 protein antibody, Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) antibody, amyloidogenic glycoprotein antibody, amyloid precursor protein antibody, amyloid protein antibody, appi antibody, appican antibody, app-PH antibody, app-PI antibody, app-PJ antibody, app-PK antibody, app-PL antibody, app-PM antibody, app-PO antibody, app-PP antibody, app-PQ antibody, approximated antibody, beta-amyloid peptide antibody, beta-amyloid precursor protein antibody, beta-amyloid precursor protein A antibody, betaApp antibody, BOS_589 antibody, cerebral vascular amyloid peptide antibody, CG42318-PH antibody, CG42318-PI antibody, CG42318-PJ antibody, CG42318-PK antibody, CG42318-PL antibody, CG42318-PM antibody, CG42318-PO antibody, CG42318-PP antibody, CG42318-PQ antibody, CR32097 antibody, CTFgamma antibody, CVAP antibody, Dmel_CG17144 antibody, Dmel_CG42318 antibody, Dmel_CG5620 antibody, peptidase nexin-II antibody, pn2 antibody, PN-II antibody, preA4 antibody, protease nexin II antibody, protease nexin-II antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen Amyloid beta 40 antibody was raised in Mouse using a synthetic target peptide as the immunogen

Images

Western Blot analysis using Amyloid beta 40 antibody (10R-8435)

Specifications

Host Mouse
Clone 32A1
Isotype IgG2b kappa
Method of Purification Amyloid beta 40 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Amyloid beta (Abeta or A beta) is a protein fragment of 39-43 amino acids that is the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Abeta is formed after sequential cleavage of the amyloid precursor protein (APP, transmembrane glycoprotein) by the beta- and gamma-secretases. . The major species generated are Abeta40 and Abeta42. The latter is more hydrophobic and more apt to aggregate and thus is considered to be primarily pathogenic, consistent with the phenotype of the major familial AD-causing mutations. Increases in either total Abeta levels or the relative concentration of the 42-amino acid form have been implicated in the pathogenesis of both familial and sporadic Alzheimer's disease. The 42-mers are the most amyloidogenic form of the peptide.

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Images

  • Western Blot analysis using Amyloid beta 40 antibody (10R-8435) |

Availability: In stock

Price: $295.00
Size: 100 ul
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