Amyloid Fibrils antibody (20R-2838)

Rabbit polyclonal Amyloid Fibrils antibody

Synonyms Polyclonal Amyloid Fibrils antibody, Anti-Amyloid Fibrils antibody, Fibril antibody, Fibrils antibody, Amyloid antibody
Applications Dot Blot, ELISA, IHC, WB
Immunogen Amyloid Fibrils antibody was raised in Rabbit using fibrils prepared from human AB42 peptide as the immunogen

Images

Dot Blot analysis using Amyloid Fibrils antibody (20R-2838)

Dot blot analysis of Abeta42 and polyQ36 prefibrillar oligomers and fibrils. Abeta42 and polyQ fibrils stain with serum (OC), while Abeta42 and polyQ prefibrillar oligomers react with A11.

Specifications

Host Rabbit
Form & Buffer Supplied in PBS buffer, pH 7.0, 0.09% sodium azide and 50% glycerol
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations ELISA: 1-10 ug/ml, IHC: 1-5 ug/ml, Dot Blot: 0.5-1 ug/ml, WB: 1-2 ug/ml

General Information

Biological Significance Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body. These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that, abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders.

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Images

  • <div><font face=Calibri size=2>Dot Blot analysis using Amyloid Fibrils antibody (20R-2838)</font></div>     | Dot blot analysis of Abeta42 and polyQ36 prefibrillar oligomers and fibrils. Abeta42 and polyQ fibrils stain with serum (OC), while Abeta42 and polyQ prefibrillar oligomers react with A11.
  • <div><font face=Calibri size=2>Immunohistochemical staining using Amyloid Fibrils antibody (20R-2838)</font></div>     | Labelling of amyloid fibrils was observed in the hippocampus (A), subiculum (B) and frontal cortex (C) in Alzheimer disease. A higher magnification photograph illustrates that amyloid fibril deposits were dense and consisted of fine fibrillar material (D).

Availability: In stock

Price: $220.00
Size: 50 ul
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