ANAPC2 antibody (10R-3304)

Mouse monoclonal ANAPC2 antibody

Synonyms Monoclonal ANAPC2 antibody, Anti-ANAPC2 antibody, Anaphase promoting complex subunit 2 antibody, APC2 antibody, KIAA1406 antibody, Cyclosome subunit 2 antibody, Anaphase promoting complex subunit 2 antibody, ANAPC2, ANAPC 2, ANAPC-2, ANAPC 2 antibody, ANAPC-2 antibody
Cross Reactivity Human
Applications FC, IF, WB
Immunogen ANAPC2 antibody was raised in mouse using a full length recombinant protein of human ANAPC2 (NP_037498) produced in HEK293T cells, as the immunogen.

Images

Flow Cytometric analysis using ANAPC2 antibody (10R-3304)

Flow Cytometric analysis of HEK293T cells transfected with either recombinant ANAPC2 protein (red) or empty vector (blue) stained using ANAPC2 antibody

Specifications

Host Mouse
Clone 2A1
Isotype IgG1
Method of Purification ANAPC2 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 500 ug-1 mg/ml

Usage & Assay Information

Usage Recommendations FC: 1:100, IF: 1:100, WB: 1:200-500

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphasetransition by ubiquitin ating its specific substrates such as mitotic cyclins and anaphase inhibitor, which aresubsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eightsubunits. The composition of the APC is highly conserved in organisms from yeast to humans. ANAPC2 is a component of the complex and shares sequence similarity with a recently identified family of proteins calledcullins, which may also be involved in ubiquitin-mediated degradation.

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Images

  • Flow Cytometric analysis using ANAPC2 antibody (10R-3304) | Flow Cytometric analysis of HEK293T cells transfected with either recombinant ANAPC2 protein (red) or empty vector (blue) stained using ANAPC2 antibody
  • Western Blot analysis using ANAPC2 antibody (10R-3304) | Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ANAPC2 protein (Right) or empty vector (Left) detected with ANAPC2 antibody
  • Immunofluorescent staining using ANAPC2 antibody (10R-3304) | Immunofluorescent staining of COS7 cells transiently transfected with recombinant ANAPC2 protein using ANAPC2 antibody

Availability: In stock

Price: $395.00
Size: 100 ul
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