Angiopoietin 1 antibody (20R-AR013)

Rabbit polyclonal Angiopoietin 1 antibody

Synonyms Polyclonal Angiopoietin 1 antibody, Anti-Angiopoietin 1 antibody, Angiopoietin 1, Angiopoietin -1, Angiopoietin -1 antibody, ANG1 antibody, KIAA0003 antibody, AGPT antibody, ANG 1 antibody, Angiopoietin1 antibody, AGP 1 antibody, ANGPT 1 antibody, ANGPT1 antibody, AGP1 antibody, Angiopoietin 1 antibody, Angiopoietin 1
Specificity Murine angiopoietin 1
Cross Reactivity Human
Applications ELISA, WB
Immunogen Angiopoietin 1 antibody was raised in rabbit using a synthetic peptide corresponding to a region near the N-terminus of mouse angiopoietin 1 protein conjugated to KLH as the immunogen.

Specifications

Host Rabbit
Form & Buffer 0.02M K3PO4, pH 7.2, with 0.15M NaCl, and 0.01% NaN3.
Concentration 85.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:5,000-1:25,000, WB: 1:500-1:2,000

Storage & Safety

Storage Store at -20 deg C. Aliquot and freeze at -20 deg C or below for long term storage. This product is stable for several weeks at 4 deg C as an undiluted liquid. Dilute only prior to immediate use. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Angiopoeitin-1 (Ang-1) and Angiopoietin-2 (Ang-2) have importance in the development of the endothelium by regulating tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding, and thus blocks receptor phosphorylation. Ang-1 has a potential fibrinogen-like domain at the carboxyl terminus and coiled-coil regions in the amino terminus. Ang-1 is prominently expressed in the myocardium of atrium and ventricle, mesenchymal and smooth muscle cells surrounding most blood vessels, and lung. In the adult, Ang-1 is also expressed in the heart and liver.

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Availability: In stock

Price: $495.00
Size: 200 ul
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