Angiopoietin 2 protein (30R-3254)

Purified recombinant Angiopoietin 2 protein

Synonyms ANG2 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 58 bp
Form & Buffer Supplied in liquid form in 6M guanidine hydrochloride and 20mM Tris buffer

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance Angiopoietin 2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

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Availability: In stock

Price: $210.00
Size: 50 ug
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