Red blood cells (RBCs), also known as Erythrocytes, are responsible for oxygen transport in the blood. Their unique shape is ideal for this function. RBCs are biconcaved discs. This shape increases the surface area-to-volume ratio of the cell, thus increasing the efficiency of diffusion of oxygen and carbon dioxide into and out of the cell. Red blood cells also have a flexible plasma membrane. This feature allows them to squeeze through the smallest of capillaries.
Red blood cells contain large amounts of hemoglobin, the protein that binds oxygen. In order to make room for more hemoglobin to carry more oxygen, RBCs sacrifice their nucleus and other organelles as they develop in the bone marrow. Because they lack a nucleus and other cellular machinery, red blood cells cannot repair themselves when damaged, consequently they have a limited life span of about 120 days. The removal of old RBCs is carryied out by the spleen.
Porcine blood, also known as Pig blood or Swine blood encapsulates many of the characteristics of human blood and is a useful animal model in many areas of research.
Fitzgerald Industries offers glutaraldehyde-stabilized freshly prepared Pig Red Blood Cells. Washing with glutaraldehyde buffer stabilizes the RBCs and increases their resistance to lysis, freeze-thawing and hemolysis. We also supply Porcine blood specific antibodies; Pig RBC antibody in unconjugated form as well as a Pig RBC antibody FITC conjugate and a Pig RBC antibody Texas Red conjugate for use in Immunofluorescence, immunohistochemistry and FACS.