EGFR antibodies or Epidermal Growth Factor Receptor antibodies are used to study cell proliferation pathways in cancer. EGFR is a transmembrane glycoprotein and a member of the protein kinase superfamily. EGFR is the main receptor for members of the epidermal growth factor family. Binding of the EGFR protein to the receptor induces receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Mutations in EGFR have been associated with several carcinomas including lung cancer. Constant activation of the epidermal growth factor receptor leads to uncontrolled cellular proliferation. Several anti cancer therapies have been developed and directed against EGFR including a range of monoclonal antibody inhibitors.
As an important regulator of cellular growth and development as well as a promising oncogene target for cancer therapies, EGFR is a widely studied member of the member of the ErbB family of receptors. Fitzgerald Industries offers a wide range of monoclonal and polyclonal EGFR antibodies for use in ELISA, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and more. Our high quality EGFR antibodies are the ideal choice for use in existing diagnostic procedures or the development of new assays. Some of our most popular EGFR antibodies include:
EGFR antibody - This sheep polyclonal EGFR antibody is protein G purified and rated for use in several applications including Immunocytochemistry, Immunocytochemistry, Immunoprecipitation, Western Blot and Immunofluorescence.
|Immunofluorescently labelled cells with sheep anti-EGFR antibody|
EGFR antibody - This purified monoclonal EGFR antibody is highly specific for human EGFR and is also recommended for use in Immunohistochemistry, Immunocytochemistry, Immunoprecipitation, Western Blot.
EGFR antibody (Alexa Fluor 488) - This conjugated epidermal growth factor receptor antibody is attached to an Alexa Fluor tag making it the ideal choice for Immunofluorescence applications.