ANXA13 protein (His tag) (80R-1771)
Purified recombinant Human ANXA13 protein
|Synonyms||ANXA-13, Annexin-13 protein, ISA protein, ANXA13, ANXA 13 protein, ANXA-13 protein, Annexin A13 protein, ANXA 13, ANX13 protein|
Coomassie Blue stained SDS-PAGE of ANXA13 protein (His tag) (80R-1771)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-316 amino acids: MGSSHHHHHH SSGLVPRGSH MGNRHAKASS PQGFDVDRDA KKLNKACKGM GTNEAAIIEI LSGRTSDERQ QIKQKYKATY GKELEEVLKS ELSGNFEKTA LALLDRPSEY AARQLQKAMK GLGTDESVLI EVLCTRTNKE IIAIKEAYQR LFDRSLESDV KGDTSGNLKK ILVSLLQANR NEGDDVDKDL AGQDAKDLYD AGEGRWGTDE LAFNEVLAKR SYKQLRATFQ AYQILIGKDI EEAIEEETSG DLQKAYLTLV RCAQDCEDYF AERLYKSMKG AGTDEETLIR IVVTRAEVDL QGIKAKFQEK YQKSLSDMVR SDTSGDFRKL LVALLH|
|Purity||> 90% pure|
|Molecular Weight||37.5 kDa (336aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol, 0.1M NaCl and 1mM EDTA.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Annexin A13, also known as ANXA13, is a member of the annexin protein family. Members of the annexin family play a role in cytoskeletal interactions, phospholipase inhibition, regulation of cellular growth, and intracellular signal transduction pathways. ANXA13 is considered the original progenitor of the 12 members of vertebrate annexins. The expression of ANXA13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Recombinant human ANXA13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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