APBA1 antibody (70R-10555)

Affinity purified rabbit polyclonal APBA1 antibody

Synonyms Polyclonal APBA1 antibody, Anti-APBA1 antibody, APBA 1, A4 precursor protein-binding, X11A antibody, X11 antibody, APBA 1 antibody, family A, APBA-1 antibody, member 1, D9S411E antibody, X11ALPHA antibody, APBA1, X11 antibody, APBA-1, MINT1 antibody, amyloid beta
Cross Reactivity Human
Applications IHC, WB
Immunogen APBA1 antibody was raised in rabbit using the N terminal of APBA1 as the immunogen
Assay Information APBA1 Blocking Peptide, catalog no. 33R-7273, is also available for use as a blocking control in assays to test for specificity of this APBA1 antibody

Images

Immunohistochemical staining using APBA1 antibody (70R-10555)

APBA1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of intestinal villus (arrows) in Human Intestine. Magnification is at 400X.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

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Images

  • Immunohistochemical staining using APBA1 antibody (70R-10555) | APBA1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of intestinal villus (arrows) in Human Intestine. Magnification is at 400X.
  • Western Blot analysis using APBA1 antibody (70R-10555) | APBA1 antibody (70R-10555) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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