APEX1 antibody (10-B9133MD02-D0)

Mouse monoclonal Apurinic/Apyrimidinic Endonuclease antibody

Synonyms Monoclonal Apurinic/Apyrmidinic-Endonuclease antibody, Monoclonal APEX1 antibody, APEX1 antibody, APEX-1 antibody, Anti APEX1 antibody, APEX1, Apurinic/Apyrmidinic-Endonuclease antibody, Anti Apurinic/Apyrmidinic-Endonuclease antibody, APEX-1, APEX 1, APEX 1 antibody
Applications User optimized

Specifications

Host Mouse
Clone 2
Concentration 2.9 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Apurinic/apyrimidinic (AP) endonuclease is an enzyme that is involved in the DNA base excision repair pathway (BER). Its main role in the repair of damaged or mismatched nucleotides in DNA is to create a nick in the phosphodiester backbone of the AP site created when DNA glycosylase removes the damaged base. There are four types of AP endonucleases that have been classified according to their sites of incision. Class I and class II AP endonucleases incise DNA at the phosphate groups 3´ and 5´ to the baseless site leaving 3´-OH and 5´-phosphate termini. Class III and class IV AP endonucleases also cleave DNA at the phosphate groups 3´ and 5´to the baseless site, but they generate a 3´-phosphate and a 5´-OH.

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Availability: In stock

Price: $150.00
Size: 1 mg
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