Apg5 antibody (70R-12163)

Rabbit polyclonal Apg5 antibody

Synonyms Polyclonal Apg5 antibody, anti-Apg5 antibody, atg-5 antibody, Apoptosis-specific protein antibody, Apg-5, autophagy protein antibody, Apg 5 antibody, Apg5, apg-5 antibody, Apg 5, Autophagy protein 5 antibody, Apg-5 antibody, APG5-like antibody, hAPG5 antibody
Cross Reactivity Human, Mouse, Rat, Pig, Bovine
Applications WB
Immunogen Apg5 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 226 of rat Apg5 as the immunogen.
Assay Information Apg5 Blocking Peptide, catalog no. 33R-10975, is also available for use as a blocking control in assays to test for specificity of this Apg5 antibody

Images

Western Blot analysis using Apg5 antibody (70R-12163)

Western blot analysi s of Apg5/Atg5 in Jurkat cell lysate.

Specifications

Host Rabbit
Isotype IgG
Method of Purification Apg5 antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer containing 30% glycerol, 0.5% BSA and 0.01% thimerosal
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.5-4 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. An ubiquitin like conjugation system is involve in the formation of autophagosome where by Atg12 is covanletly bound to Apg5/ATG5. The conjugation is mediated by the ubiquitin-E1-like enzyme Atg7 and thE2-like enzyme Atg10.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using Apg5 antibody (70R-12163)</font></div>     | Western blot analysi s of Apg5/Atg5 in Jurkat cell lysate.

Availability: In stock

Price: $335.00
Size: 100 ug
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