ARNTL antibody (10R-1418)

Mouse monoclonal ARNTL antibody

Synonyms Monoclonal ARNTL antibody, Anti-ARNTL antibody, BMAL1c antibody, MOP3 antibody, BMAL1 antibody, PASD3 antibody, JAP3 antibody, TIC antibody, MGC47515 antibody, Aryl hydrocarbon receptor nuclear translocator-like antibody
Specificity Human ARNTL
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen ARNTL antibody was raised in mouse using recombinant Human Aryl Hydrocarbon Receptor Nuclear Translocator-Like

Images

Western Blot analysis of immunized recombinant protein using ARNTL antibody (10R-1418)

Specifications

Host Mouse
Clone 621C3a
Isotype IgG1
Method of Purification ARNTL antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer ARNTL antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Aryl hydrocarbon receptor nuclear translocator-like, also known as ARNTL, Bmal1, or Mop3, is a gene which is associated with susceptibility to hypertension and type 2 diabetes. The protein encoded by this gene is a basic-helix-loop-helix PAS (bHLH-PAS) domain containing protein that forms a heterodimer with a second bHLH-PAS protein, Clock, or its ortholog, Npas2. This complex binds to E-box response elements in promoter regions of many genes including those encoding the Period (Per1, Per2, Per3) and Cryptochrome (Cry1 and Cry2) proteins.

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Images

  • Western Blot analysis of immunized recombinant protein using ARNTL antibody (10R-1418)

Availability: In stock

Price: $190.00
Size: 50 ug
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