ARPP19 protein (His tag) (80R-3582)

Purified recombinant ARPP19 protein (His tag)

Synonyms ARPP-16 protein, ARPP-19 protein, ARPP16 protein, ENSAL protein, ARPP 19 protein, ARPP-19 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie blue stained SDS-PAGE of ARPP19 protein (His tag) (80R-3582)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-112 aa: MGSSHHHHHH SSGLVPRGSH MGSMSAEVPE AASAEEQKEM EDKVTSPEKA EEAKLKARYP HLGQKPGGSD FLRKRLQKGQ KYFDSGDYNM AKAKMKNKQL PTAAPDKTEV TGDHIPTPQD LPQRKPSLVA SKLAG
Expression System E.coli
Purity > 90% pure
Method of Purification ARPP19 protein was purified by using conventional chromatography techniques
Molecular Weight 14.7 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Concentration 500 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance cAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression.

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Images

  • Coomassie blue stained SDS-PAGE of ARPP19 protein (His tag) (80R-3582) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $275.00
Size: 100 ug
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