ATF2 antibody (70R-14943)

Rabbit polyclonal ATF2 antibody

Synonyms Polyclonal ATF2 antibody, Anti-ATF2 antibody, ATF 2 antibody, ATF-2 antibody, Activating Transcription Factor 2 antibody
Applications IHC, WB

Images

Western Blot analysis using ATF2 antibody (70R-14943)

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of ~74k ATF2 protein phosphorylated at Ser236 and Ser498

Specifications

Host Rabbit
Method of Purification ATF2 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:1000

General Information

Biological Significance ATF2 is a transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.

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Images

  • Western Blot analysis using ATF2 antibody (70R-14943) | Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immunolabeling of ~74k ATF2 protein phosphorylated at Ser236 and Ser498

Availability: In stock

Price: $335.00
Size: 100 ul
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