ATF3 protein (30R-2076)

Purified recombinant ATF3 protein

Synonyms ATF 3, ATF-3 protein, ATF 3 protein, ATF3, ATF-3, Cyclic AMP dependent transcription factor ATF3 protein, ATF3deltaZip3 protein, ATF3deltaZip2 protein, cAMP dependent transcription factor ATF3 protein, ATF3deltaZip2c protein, Cyclic AMP-dependent transcription factor ATF-3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of ATF3 protein (30R-2076)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-181 amino acids: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
Expression System E.coli
Purity > 90% pure
Molecular Weight 20.6kDa (181aa)
Form & Buffer Supplied as a liquid in 20mM Tris-HCl, pH 8.0, containing 2M Urea and 20% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.

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Images

  • Coomassie Blue stained SDS-PAGE of ATF3 protein  (30R-2076) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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