ATP7A antibody (70R-1151)
Rabbit polyclonal ATP7A antibody
|Synonyms||Polyclonal ATP7A antibody, Anti-ATP7A antibody, MNK antibody, MK antibody, Atpase Cu++ Transporting Alpha Polypeptide antibody, Menkes syndrome antibody|
|Immunogen||ATP7A antibody was raised using a synthetic peptide corresponding to a region with amino acids MKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYQ|
Western Blot analysis using ATP7A antibody (70R-1151)
ATP7A antibody (70R-1151) used at 2.5 ug/ml to detect target protein.
|Method of Purification||Total IgG Protein A purified|
|Molecular Weight||30 kDa (MW of target protein)|
|Form & Buffer||Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of ATP7A antibody in PBS|
Usage & Assay Information
|Usage Recommendations||WB: 2.5 ug/ml|
Storage & Safety
|Storage||Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.|
|Biological Significance||The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.|
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